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Prescription Oral Weight Management

Contrave® in Tampa , FL

Meet with an Oceans provider to discuss whether Contrave®, a prescription combination of naltrexone and bupropion, may be appropriate for your long-term weight-management plan.

Patient discussing Contrave oral weight-management treatment
Two Medicines, One Tablet Contrave® combines naltrexone and bupropion in an extended-release oral medication.
Provider Evaluation
Oral Medication
Personalized Plan
Ongoing Monitoring
About Contrave®

A Non-GLP-1 Prescription Option

Contrave® is an FDA-approved prescription medication used with a reduced-calorie diet and increased physical activity for chronic weight management in eligible adults. It does not contain semaglutide, tirzepatide, or another GLP-1 medication.

Craving and Appetite Support

The medication acts on pathways in the brain involved in appetite and reward-related eating behavior.

Oral Treatment

Contrave® is an extended-release tablet taken according to a gradual provider-directed dosing schedule.

Clinical Monitoring

Providers should monitor response, blood pressure, heart rate, mood changes, side effects, and medication interactions.

Women exercising as part of a healthy weight-management plan
The Oceans Process

How to Get Started

1
Complete Your Medical HistoryShare your medications, opioid use, seizure history, blood-pressure history, eating-disorder history, mood symptoms, and weight-management goals.
2
Meet With a ProviderYour provider reviews eligibility, contraindications, drug interactions, risks, alternatives, and whether oral treatment fits your plan.
3
Begin a Monitored PlanWhen appropriate, your provider explains the titration schedule, follow-up requirements, lifestyle recommendations, and when treatment response should be reassessed.
Schedule Your Visit
How Contrave® Works

Naltrexone and Bupropion

Each component has a different clinical role. Their combination may help certain eligible adults manage appetite and cravings when used as part of a broader treatment plan.

Naltrexone

Naltrexone is an opioid antagonist. In Contrave®, it is used as part of the combination’s effect on appetite and reward pathways.

  • Can block the effects of opioid medications
  • Requires careful review of current and recent opioid use
  • May complicate pain treatment if opioid analgesia is needed

Bupropion

Bupropion affects norepinephrine and dopamine pathways and is also used in other products for depression or smoking cessation.

  • Can increase seizure risk in susceptible patients
  • May increase blood pressure or heart rate
  • Should not be combined with other bupropion-containing products

Contrave® must be prescribed and monitored by a licensed clinician. Do not start, stop, or change opioid, antidepressant, or other medications without discussing the change with the prescribing provider.

Oceans medical weight-management program
Personalized Medical Support

Your Program May Include

Prescription treatment works best as part of a structured plan that addresses nutrition, activity, behaviors, health conditions, and ongoing progress.

Medical-history review
Medication-interaction review
Blood-pressure monitoring
Gradual dose titration
Response assessment
Lifestyle guidance
Request an Appointment
Frequently Asked Questions

Contrave® FAQ

What medications are in Contrave®?

Contrave® contains extended-release naltrexone and bupropion in a fixed-dose combination tablet.

Is Contrave® a GLP-1 medication?

No. Contrave® is an oral naltrexone/bupropion combination and does not contain semaglutide or tirzepatide.

How is treatment response evaluated?

The prescribing information includes a defined reassessment point after the patient reaches the maintenance dose. Your provider should determine whether continued treatment is appropriate based on response and tolerability.

Can I take Contrave® with Wellbutrin®?

No. Contrave® already contains bupropion and should not be combined with another bupropion-containing medication.

Start With a Medical Evaluation

Book Your Contrave® Consultation

Meet with an Oceans provider in Tampa to discuss eligibility, and a personalized treatment plan.

Book an Appointment

Contrave® is a registered trademark of its respective owner. Oceans Weight Loss & Med Spa is not represented as affiliated with or endorsed by the trademark owner. Prescription treatment requires a medical evaluation and is provided only when clinically appropriate. Results vary. This page is for general education and does not replace individualized medical advice. Review the current FDA-approved prescribing information and Medication Guide with your clinician.

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